β-Catenin Regulates Positive Selection of Thymocytes but Not Lineage Commitment
نویسندگان
چکیده
منابع مشابه
Regulation of NK1.1 expression during lineage commitment of progenitor thymocytes.
We recently identified a stage in fetal ontogeny (NK1.1+/CD117+) that defines committed progenitors for T and NK lymphocytes. These cells are found in the fetal thymus as early as day 13 of gestation, but are absent in the fetal liver. Nonetheless, multipotent precursors derived from both the fetal thymus and fetal liver are capable of rapidly differentiating to the NK1.1+ stage upon transfer i...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2007
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.178.8.5028